2-mercaptobenzothiazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5522 | 149-30-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| FDA CS | M0000728 | Allergens |
| FDA PE | N0000175629 | Increased Histamine Release |
| FDA PE | N0000184306 | Cell-mediated Immunity |
| FDA EPC | N0000185508 | Standardized Chemical Allergen |
| CHEBI has role | CHEBI:25212 | metabolites |
| CHEBI has role | CHEBI:50903 | carcinogen |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Dogs | Moist Dermatitis | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Sulfodene Medication for Dogs | Farnam Companies Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Proteasome subunit beta type-8 | Enzyme | IC50 | 4.89 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| CHEBI:34292 | CHEBI |
| CHEMBL111654 | ChEMBL_ID |
| DB11496 | DRUGBANK_ID |
| 016111 | NDDF |
| C0054631 | UMLSCUI |
| XO9 | PDB_CHEM_ID |
| 411136000 | SNOMEDCT_US |
| 96039001 | SNOMEDCT_US |
| C14437 | KEGG_DRUG |
| 697993 | PUBCHEM_CID |
| 1358845 | RXNORM |
| 5RLR54Z22K | UNII |
Pharmaceutical products:
None